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UNC5C Receptor Proteolytic Cleavage by Active AEP Promotes Dopaminergic Neuronal Degeneration in Parkinson's Disease
Netrin‐1 is a chemotropic cue mediating axon growth and neural migration in neuronal development, and its receptors deletion in colorectal cancer and UNC5s act as dependence receptors regulating neuronal apoptosis. Asparagine endopeptidase (AEP) is an age‐dependent protease that cuts human alpha‐syn...
Autores principales: | Chen, Guiqin, Ahn, Eun Hee, Kang, Seong Su, Xia, Yiyuan, Liu, Xia, Zhang, Zhaohui, Ye, Keqiang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8895126/ https://www.ncbi.nlm.nih.gov/pubmed/35023303 http://dx.doi.org/10.1002/advs.202103396 |
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