Simvastatin Downregulates the SARS-CoV-2-Induced Inflammatory Response and Impairs Viral Infection Through Disruption of Lipid Rafts

Coronavirus disease 2019 (COVID-19) is currently a worldwide emergency caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). In observational clinical studies, statins have been identified as beneficial to hospitalized patients with COVID-19. However, experimental evidence of under...

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Detalles Bibliográficos
Autores principales: Teixeira, Lívia, Temerozo, Jairo R., Pereira-Dutra, Filipe S., Ferreira, André Costa, Mattos, Mayara, Gonçalves, Barbara Simonson, Sacramento, Carolina Q., Palhinha, Lohanna, Cunha-Fernandes, Tamires, Dias, Suelen S. G., Soares, Vinicius Cardoso, Barreto, Ester A., Cesar-Silva, Daniella, Fintelman-Rodrigues, Natalia, Pão, Camila R. R., de Freitas, Caroline S., Reis, Patrícia A., Hottz, Eugenio D., Bozza, Fernando A., Bou-Habib, Dumith C., Saraiva, Elvira M., de Almeida, Cecília J. G., Viola, João P. B., Souza, Thiago Moreno L., Bozza, Patricia T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8895251/
https://www.ncbi.nlm.nih.gov/pubmed/35251001
http://dx.doi.org/10.3389/fimmu.2022.820131

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