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Cuprizone Intoxication Results in Myelin Vacuole Formation

Myelin damage is a histopathological hallmark of multiple sclerosis lesions. Results of post mortem studies suggest that impaired myelin-axon interaction characterized by focal myelin detachments is an early event during lesion genesis. In this study, we investigated the ultrastructural changes of t...

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Detalles Bibliográficos
Autores principales: Joost, Sarah, Schweiger, Felix, Pfeiffer, Friederike, Ertl, Carolin, Keiler, Jonas, Frank, Marcus, Kipp, Markus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8895267/
https://www.ncbi.nlm.nih.gov/pubmed/35250482
http://dx.doi.org/10.3389/fncel.2022.709596