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Rapid synchronous type 1 IFN and virus-specific T cell responses characterize first wave non-severe SARS-CoV-2 infections

Effective control of SARS-CoV-2 infection on primary exposure may reveal correlates of protective immunity to future variants, but we lack insights into immune responses before or at the time virus is first detected. We use blood transcriptomics, multiparameter flow cytometry, and T cell receptor (T...

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Detalles Bibliográficos
Autores principales: Chandran, Aneesh, Rosenheim, Joshua, Nageswaran, Gayathri, Swadling, Leo, Pollara, Gabriele, Gupta, Rishi K., Burton, Alice R., Guerra-Assunção, José Afonso, Woolston, Annemarie, Ronel, Tahel, Pade, Corinna, Gibbons, Joseph M., Sanz-Magallon Duque De Estrada, Blanca, Robert de Massy, Marc, Whelan, Matthew, Semper, Amanda, Brooks, Tim, Altmann, Daniel M., Boyton, Rosemary J., McKnight, Áine, Captur, Gabriella, Manisty, Charlotte, Treibel, Thomas Alexander, Moon, James C., Tomlinson, Gillian S., Maini, Mala K., Chain, Benjamin M., Noursadeghi, Mahdad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8895494/
https://www.ncbi.nlm.nih.gov/pubmed/35474751
http://dx.doi.org/10.1016/j.xcrm.2022.100557