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Predicting molecular initiating events using chemical target annotations and gene expression

BACKGROUND: The advent of high-throughput transcriptomic screening technologies has resulted in a wealth of publicly available gene expression data associated with chemical treatments. From a regulatory perspective, data sets that cover a large chemical space and contain reference chemicals offer ut...

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Detalles Bibliográficos
Autores principales:	Bundy, Joseph L., Judson, Richard, Williams, Antony J., Grulke, Chris, Shah, Imran, Everett, Logan J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8895536/ https://www.ncbi.nlm.nih.gov/pubmed/35246223 http://dx.doi.org/10.1186/s13040-022-00292-z

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