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MiR-25 overexpression inhibits titanium particle-induced osteoclast differentiation via down-regulation of mitochondrial calcium uniporter in vitro
BACKGROUND: Mitochondrial calcium uniporter (MCU) is an important ion channel regulating calcium transport across the mitochondrial membrane. Calcium signaling, particularly via the Ca(2+)/NFATc1 pathway, has been identified as an important mediator of the osteoclast differentiation that leads to os...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8895597/ https://www.ncbi.nlm.nih.gov/pubmed/35241114 http://dx.doi.org/10.1186/s13018-022-03030-7 |