MiR-25 overexpression inhibits titanium particle-induced osteoclast differentiation via down-regulation of mitochondrial calcium uniporter in vitro

BACKGROUND: Mitochondrial calcium uniporter (MCU) is an important ion channel regulating calcium transport across the mitochondrial membrane. Calcium signaling, particularly via the Ca(2+)/NFATc1 pathway, has been identified as an important mediator of the osteoclast differentiation that leads to os...

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Detalles Bibliográficos
Autores principales: Hu, Weifan, Yu, Yongbo, Sun, Yang, Yuan, Feng, Zhao, Fengchao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8895597/
https://www.ncbi.nlm.nih.gov/pubmed/35241114
http://dx.doi.org/10.1186/s13018-022-03030-7

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