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Evidence against Zika virus infection of pets and peri-domestic animals in Latin America and Africa

Decades after its discovery in East Africa, Zika virus (ZIKV) emerged in Brazil in 2013 and infected millions of people during intense urban transmission. Whether vertebrates other than humans are involved in ZIKV transmission cycles remained unclear. Here, we investigate the role of different anima...

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Autores principales: de Oliveira-Filho, Edmilson F., Carneiro, Ianei O., Fischer, Carlo, Kühne, Arne, Postigo-Hidalgo, Ignacio, Ribas, Jorge R. L., Schumann, Peggy, Nowak, Kathrin, Gogarten, Jan F., de Lamballerie, Xavier, Dantas-Torres, Filipe, Netto, Eduardo Martins, Franke, Carlos Roberto, Couacy-Hymann, Emmanuel, Leendertz, Fabian H., Drexler, Jan Felix
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Microbiology Society 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8895617/
https://www.ncbi.nlm.nih.gov/pubmed/35077341
http://dx.doi.org/10.1099/jgv.0.001709
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author de Oliveira-Filho, Edmilson F.
Carneiro, Ianei O.
Fischer, Carlo
Kühne, Arne
Postigo-Hidalgo, Ignacio
Ribas, Jorge R. L.
Schumann, Peggy
Nowak, Kathrin
Gogarten, Jan F.
de Lamballerie, Xavier
Dantas-Torres, Filipe
Netto, Eduardo Martins
Franke, Carlos Roberto
Couacy-Hymann, Emmanuel
Leendertz, Fabian H.
Drexler, Jan Felix
author_facet de Oliveira-Filho, Edmilson F.
Carneiro, Ianei O.
Fischer, Carlo
Kühne, Arne
Postigo-Hidalgo, Ignacio
Ribas, Jorge R. L.
Schumann, Peggy
Nowak, Kathrin
Gogarten, Jan F.
de Lamballerie, Xavier
Dantas-Torres, Filipe
Netto, Eduardo Martins
Franke, Carlos Roberto
Couacy-Hymann, Emmanuel
Leendertz, Fabian H.
Drexler, Jan Felix
author_sort de Oliveira-Filho, Edmilson F.
collection PubMed
description Decades after its discovery in East Africa, Zika virus (ZIKV) emerged in Brazil in 2013 and infected millions of people during intense urban transmission. Whether vertebrates other than humans are involved in ZIKV transmission cycles remained unclear. Here, we investigate the role of different animals as ZIKV reservoirs by testing 1723 sera of pets, peri-domestic animals and African non-human primates (NHP) sampled during 2013–2018 in Brazil and 2006–2016 in Côte d'Ivoire. Exhaustive neutralization testing substantiated co-circulation of multiple flaviviruses and failed to confirm ZIKV infection in pets or peri-domestic animals in Côte d'Ivoire (n=259) and Brazil (n=1416). In contrast, ZIKV seroprevalence was 22.2% (2/9, 95% CI, 2.8–60.1) in West African chimpanzees (Pan troglodytes verus) and 11.1% (1/9, 95% CI, 0.3–48.3) in king colobus (Colobus polycomos). Our results indicate that while NHP may represent ZIKV reservoirs in Africa, pets or peri-domestic animals likely do not play a role in ZIKV transmission cycles.
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spelling pubmed-88956172022-03-04 Evidence against Zika virus infection of pets and peri-domestic animals in Latin America and Africa de Oliveira-Filho, Edmilson F. Carneiro, Ianei O. Fischer, Carlo Kühne, Arne Postigo-Hidalgo, Ignacio Ribas, Jorge R. L. Schumann, Peggy Nowak, Kathrin Gogarten, Jan F. de Lamballerie, Xavier Dantas-Torres, Filipe Netto, Eduardo Martins Franke, Carlos Roberto Couacy-Hymann, Emmanuel Leendertz, Fabian H. Drexler, Jan Felix J Gen Virol Animal Decades after its discovery in East Africa, Zika virus (ZIKV) emerged in Brazil in 2013 and infected millions of people during intense urban transmission. Whether vertebrates other than humans are involved in ZIKV transmission cycles remained unclear. Here, we investigate the role of different animals as ZIKV reservoirs by testing 1723 sera of pets, peri-domestic animals and African non-human primates (NHP) sampled during 2013–2018 in Brazil and 2006–2016 in Côte d'Ivoire. Exhaustive neutralization testing substantiated co-circulation of multiple flaviviruses and failed to confirm ZIKV infection in pets or peri-domestic animals in Côte d'Ivoire (n=259) and Brazil (n=1416). In contrast, ZIKV seroprevalence was 22.2% (2/9, 95% CI, 2.8–60.1) in West African chimpanzees (Pan troglodytes verus) and 11.1% (1/9, 95% CI, 0.3–48.3) in king colobus (Colobus polycomos). Our results indicate that while NHP may represent ZIKV reservoirs in Africa, pets or peri-domestic animals likely do not play a role in ZIKV transmission cycles. Microbiology Society 2022-01-25 /pmc/articles/PMC8895617/ /pubmed/35077341 http://dx.doi.org/10.1099/jgv.0.001709 Text en © 2022 The Authors https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License.
spellingShingle Animal
de Oliveira-Filho, Edmilson F.
Carneiro, Ianei O.
Fischer, Carlo
Kühne, Arne
Postigo-Hidalgo, Ignacio
Ribas, Jorge R. L.
Schumann, Peggy
Nowak, Kathrin
Gogarten, Jan F.
de Lamballerie, Xavier
Dantas-Torres, Filipe
Netto, Eduardo Martins
Franke, Carlos Roberto
Couacy-Hymann, Emmanuel
Leendertz, Fabian H.
Drexler, Jan Felix
Evidence against Zika virus infection of pets and peri-domestic animals in Latin America and Africa
title Evidence against Zika virus infection of pets and peri-domestic animals in Latin America and Africa
title_full Evidence against Zika virus infection of pets and peri-domestic animals in Latin America and Africa
title_fullStr Evidence against Zika virus infection of pets and peri-domestic animals in Latin America and Africa
title_full_unstemmed Evidence against Zika virus infection of pets and peri-domestic animals in Latin America and Africa
title_short Evidence against Zika virus infection of pets and peri-domestic animals in Latin America and Africa
title_sort evidence against zika virus infection of pets and peri-domestic animals in latin america and africa
topic Animal
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8895617/
https://www.ncbi.nlm.nih.gov/pubmed/35077341
http://dx.doi.org/10.1099/jgv.0.001709
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