Cargando…

Relationship between brain iron deposition and mitochondrial dysfunction in idiopathic Parkinson’s disease

BACKGROUND: The underlying pathophysiology of Parkinson's disease is complex, involving different molecular pathways, including brain iron deposition and mitochondrial dysfunction. At a molecular level, these disease mechanisms are likely interconnected. Therefore, they offer potential strategi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Prasuhn, Jannik, Göttlich, Martin, Gerkan, Friederike, Kourou, Sofia, Ebeling, Britt, Kasten, Meike, Hanssen, Henrike, Klein, Christine, Brüggemann, Norbert
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8895656/ https://www.ncbi.nlm.nih.gov/pubmed/35246038 http://dx.doi.org/10.1186/s10020-021-00426-9

Ejemplares similares

Increased Subcortical Sodium Levels in Patients with Progressive Supranuclear Palsy
por: Prasuhn, Jannik, et al.
Publicado: (2022)

Depressive symptoms in Parkinson’s disease are insufficiently but more often treated than in other chronic conditions
por: Usnich, Tatiana, et al.
Publicado: (2023)

Gene Therapeutic Approaches for the Treatment of Mitochondrial Dysfunction in Parkinson’s Disease
por: Prasuhn, Jannik, et al.
Publicado: (2021)

Iron- and Neuromelanin-Weighted Neuroimaging to Study Mitochondrial Dysfunction in Patients with Parkinson’s Disease
por: Pizarro-Galleguillos, Benjamin Matis, et al.
Publicado: (2022)

The Use of Vitamin K2 in Patients With Parkinson's Disease and Mitochondrial Dysfunction (PD-K2): A Theranostic Pilot Study in a Placebo-Controlled Parallel Group Design
por: Prasuhn, Jannik, et al.
Publicado: (2021)

Genotype-driven therapeutic developments in Parkinson’s disease
por: Prasuhn, Jannik, et al.
Publicado: (2021)

Clinical MR imaging in Parkinson’s disease: How useful is the swallow tail sign?
por: Prasuhn, Jannik, et al.
Publicado: (2021)

Applicability of optical coherence tomography angiography (OCTA) imaging in Parkinson’s disease
por: Lauermann, Jost L., et al.
Publicado: (2021)

Neuroinflammation and Mitochondrial Dysfunction in Parkinson’s Disease: Connecting Neuroimaging with Pathophysiology
por: Pizarro-Galleguillos, Benjamin Matís, et al.
Publicado: (2023)

An omics-based strategy using coenzyme Q10 in patients with Parkinson’s disease: concept evaluation in a double-blind randomized placebo-controlled parallel group trial
por: Prasuhn, Jannik, et al.
Publicado: (2019)

A machine learning-based classification approach on Parkinson’s disease diffusion tensor imaging datasets
por: Prasuhn, Jannik, et al.
Publicado: (2020)

Discordance in monozygotic Parkinson's disease twins – continuum or dichotomy?
por: Balck, Alexander, et al.
Publicado: (2019)

Neuroimaging Methods to Map In Vivo Changes of OXPHOS and Oxidative Stress in Neurodegenerative Disorders
por: Prasuhn, Jannik, et al.
Publicado: (2022)

Altered Resting State Brain Networks in Parkinson’s Disease
por: Göttlich, Martin, et al.
Publicado: (2013)

The Role of Rare Coding Variants in Parkinson's Disease GWAS Loci
por: Germer, Elisabeth Luisa, et al.
Publicado: (2019)

Oculomotor abnormalities indicate early executive dysfunction in prodromal X-linked dystonia-parkinsonism (XDP)
por: Mertin, Renana, et al.
Publicado: (2023)

Coffee, smoking and aspirin are associated with age at onset in idiopathic Parkinson’s disease
por: Gabbert, Carolin, et al.
Publicado: (2022)

Targeting Mitochondrial Impairment in Parkinson's Disease: Challenges and Opportunities
por: Prasuhn, Jannik, et al.
Publicado: (2021)

Transient Generalized Chorea in Influenza A Encephalopathy
por: Prasuhn, Jannik, et al.
Publicado: (2018)

Genome-Edited, TH-expressing Neuroblastoma Cells as a Disease Model for Dopamine-Related Disorders: A Proof-of-Concept Study on DJ-1-deficient Parkinsonism
por: Prasuhn, Jannik, et al.
Publicado: (2018)

On the Role of Iron in Idiopathic Parkinson’s Disease
por: Huenchuguala, Sandro, et al.
Publicado: (2023)

Epidemiology of Parkinson's disease
por: Kasten, Meike, et al.
Publicado: (2007)

Iron deposition in Parkinson’s disease by quantitative susceptibility mapping
por: Chen, Qiqi, et al.
Publicado: (2019)

Lifestyle factors and clinical severity of Parkinson’s disease
por: Gabbert, Carolin, et al.
Publicado: (2023)

Qualitative Characteristics of Depression in Parkinson's Patients and Controls
por: Kritzinger, Cleo, et al.
Publicado: (2015)

Brain iron deposition is linked with cognitive severity in Parkinson’s disease
por: Thomas, George Edward Calver, et al.
Publicado: (2020)

Modified Iron Deposition in Nigrosomes by Pharmacotherapy for the Management of Parkinson’s Disease
por: Wang, Mengdi, et al.
Publicado: (2022)

Risky behaviors and Parkinson disease: A mendelian randomization study
por: Grover, Sandeep, et al.
Publicado: (2019)

Premotor Gray Matter Volume is Associated with Clinical Findings in Idiopathic and Genetically Determined Parkinson’s Disease
por: Reetz, K, et al.
Publicado: (2008)

Correction: Brain iron deposition is linked with cognitive severity in Parkinson’s disease
Publicado: (2021)

Nigral Iron Deposition Is Associated With Levodopa-Induced Dyskinesia in Parkinson’s Disease
por: Song, Tianbin, et al.
Publicado: (2021)

Characteristics of systemic inflammation and brain iron deposition in Parkinson's disease patients
por: Xu, Jinghui, et al.
Publicado: (2022)

Motor Sequence Learning Deficits in Idiopathic Parkinson’s Disease Are Associated With Increased Substantia Nigra Activity
por: Tzvi, Elinor, et al.
Publicado: (2021)

Validity and Prognostic Value of a Polygenic Risk Score for Parkinson’s Disease
por: Koch, Sebastian, et al.
Publicado: (2021)

The Rostock International Parkinson's Disease (ROPAD) Study: Protocol and Initial Findings
por: Skrahina, Volha, et al.
Publicado: (2020)

The impact of iron deposition on the fear circuit of the brain in patients with Parkinson’s disease and anxiety
por: Chen, Kaidong, et al.
Publicado: (2023)

Mitochondrial damage-associated inflammation highlights biomarkers in PRKN/PINK1 parkinsonism
por: Borsche, Max, et al.
Publicado: (2020)

Serum Uric Acid and Nigral Iron Deposition in Parkinson’s Disease: A Pilot Study
por: Kim, Tae-Hyoung, et al.
Publicado: (2014)

Commentary: The impact of iron deposition on the fear circuit of the brain in patients with Parkinson's disease and anxiety
por: Chen, Leilei, et al.
Publicado: (2023)

Application value of multiparametric MRI for evaluating iron deposition in the substantia nigra in Parkinson's disease
por: Cao, Qing, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_v6lcl1dc53hujgoj785tn8pdtm