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Optimizing therapeutic outcomes of immune checkpoint blockade by a microbial tryptophan metabolite
BACKGROUND: Despite the great success, the therapeutic benefits of immune checkpoint inhibitors (ICIs) in cancer immunotherapy are limited by either various resistance mechanisms or ICI-associated toxic effects including gastrointestinal toxicity. Thus, novel therapeutic strategies that provide mana...
Autores principales: | , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8896050/ https://www.ncbi.nlm.nih.gov/pubmed/35236743 http://dx.doi.org/10.1136/jitc-2021-003725 |