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Optimizing therapeutic outcomes of immune checkpoint blockade by a microbial tryptophan metabolite

BACKGROUND: Despite the great success, the therapeutic benefits of immune checkpoint inhibitors (ICIs) in cancer immunotherapy are limited by either various resistance mechanisms or ICI-associated toxic effects including gastrointestinal toxicity. Thus, novel therapeutic strategies that provide mana...

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Detalles Bibliográficos
Autores principales:	Renga, Giorgia, Nunzi, Emilia, Pariano, Marilena, Puccetti, Matteo, Bellet, Marina Maria, Pieraccini, Giuseppe, D’Onofrio, Fiorella, Santarelli, Ilaria, Stincardini, Claudia, Aversa, Franco, Riuzzi, Francesca, Antognelli, Cinzia, Gargaro, Marco, Bereshchenko, Oxana, Ricci, Maurizio, Giovagnoli, Stefano, Romani, Luigina, Costantini, Claudio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2022
Materias:	Basic Tumor Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8896050/ https://www.ncbi.nlm.nih.gov/pubmed/35236743 http://dx.doi.org/10.1136/jitc-2021-003725

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