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Integration of Count Difference and Curve Similarity in Negative Regulatory Element Detection

Negative regulatory elements (NREs) down-regulate gene expression by inhibiting the activities of promoters or enhancers. The repressing activity of NREs can be measured globally by massively parallel reporter assays (MPRAs). However, most existing algorithms are designed for the statistical detecti...

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Detalles Bibliográficos
Autores principales:	He, Na, Wang, Wenjing, Fang, Chao, Tan, Yongjian, Li, Li, Hou, Chunhui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Genetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8896116/ https://www.ncbi.nlm.nih.gov/pubmed/35251128 http://dx.doi.org/10.3389/fgene.2022.818344

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