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Farnesoid X Receptor Deficiency Induces Hepatic Lipid and Glucose Metabolism Disorder via Regulation of Pyruvate Dehydrogenase Kinase 4

Farnesoid X receptors (FXR) are bile acid receptors that play roles in lipid, glucose, and energy homeostasis. Synthetic FXR-specific agonists have been developed for treating nonalcoholic fatty liver disease (NAFLD) patients. However, the detailed mechanism remains unclear. To investigate the effec...

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Detalles Bibliográficos
Autores principales:	Deng, Wenyi, Fan, Wenjing, Tang, Tingting, Wan, Hengquan, Zhao, Simin, Tan, Yao, Oware, Kwabena Agyare, Tan, Jieqiong, Li, Jiequn, Qu, Shunlin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8896157/ https://www.ncbi.nlm.nih.gov/pubmed/35251469 http://dx.doi.org/10.1155/2022/3589525

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