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Development of methodology for assessing steroid-tapering in clinical trials for biologics in asthma

BACKGROUND: Long-term use of oral corticosteroids (OCS) is associated with a risk of adverse events and comorbidities. As such, a goal in assessing the efficacy of biologics in severe asthma is often to monitor reduction in OCS usage. Importantly, however, OCS dose reductions must be conducted witho...

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Detalles Bibliográficos
Autores principales: Korn, Stephanie, Howarth, Peter, Smith, Steven G., Price, Robert G., Yancey, Steven W., Prazma, Charlene M., Bel, Elisabeth H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8896284/
https://www.ncbi.nlm.nih.gov/pubmed/35246123
http://dx.doi.org/10.1186/s12931-022-01959-1