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Traditional Chinese medicine intervention for autism spectrum disorders: A protocol for systematic review and network meta-analysis
BACKGROUND: Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by impairments in social communication, social interaction, and restrictive or repetitive behaviors. Traditional Chinese medicine (TCM) has been used in the clinical management of ASD, especially in mainland Ch...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8896422/ https://www.ncbi.nlm.nih.gov/pubmed/35244056 http://dx.doi.org/10.1097/MD.0000000000028957 |
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author | Feng, Xiang Li, Keshang Jiang, Quanrui Zhang, Yuxing Gong, Zhichao Zhi, Hui Yu, Jun Li, Wu Li, Jiangshan |
author_facet | Feng, Xiang Li, Keshang Jiang, Quanrui Zhang, Yuxing Gong, Zhichao Zhi, Hui Yu, Jun Li, Wu Li, Jiangshan |
author_sort | Feng, Xiang |
collection | PubMed |
description | BACKGROUND: Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by impairments in social communication, social interaction, and restrictive or repetitive behaviors. Traditional Chinese medicine (TCM) has been used in the clinical management of ASD, especially in mainland China, where studies have shown promising efficacy. However, this remains to be further explored and clarified. Therefore, the purpose of this study was to evaluate the effectiveness and safety of conventional treatment-based TCM interventions for ASD. METHOD: The study will be conducted from January 2022, and the following electronic databases will be searched: China Biological Medicine Database, Chinese Scientific Journals Database, Wan Fang database, and China National Knowledge Infrastructure, the Cochrane Library, Web of Science, PubMed, and EMBASE Database. Only randomized controlled trials of TCM interventions for ASD will be included. The Autism Diagnostic Observation Scale, Autism Diagnostic Interview-Revised, and Childhood Autism Rating Scale will be the primary outcome indicators. The methodological quality of this Bayesian-based network meta-analysis will be performed using the “Risk of Bias” tool. Stata 14.0 and WinBUGS 1.4.3 will be used to analyze the data. In addition, assessment of heterogeneity, inconsistency, subgroups, sensitivity, and publication bias will be conducted using the Cochrane Collaboration's tools. RESULTS: The results of this study will be submitted to a peer-reviewed journal for publication. CONCLUSION: This study will help patients recover better, provide clinical evidence for practitioners, and promote the use of TCM in ASD interventions. |
format | Online Article Text |
id | pubmed-8896422 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Lippincott Williams & Wilkins |
record_format | MEDLINE/PubMed |
spelling | pubmed-88964222022-03-07 Traditional Chinese medicine intervention for autism spectrum disorders: A protocol for systematic review and network meta-analysis Feng, Xiang Li, Keshang Jiang, Quanrui Zhang, Yuxing Gong, Zhichao Zhi, Hui Yu, Jun Li, Wu Li, Jiangshan Medicine (Baltimore) 3800 BACKGROUND: Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by impairments in social communication, social interaction, and restrictive or repetitive behaviors. Traditional Chinese medicine (TCM) has been used in the clinical management of ASD, especially in mainland China, where studies have shown promising efficacy. However, this remains to be further explored and clarified. Therefore, the purpose of this study was to evaluate the effectiveness and safety of conventional treatment-based TCM interventions for ASD. METHOD: The study will be conducted from January 2022, and the following electronic databases will be searched: China Biological Medicine Database, Chinese Scientific Journals Database, Wan Fang database, and China National Knowledge Infrastructure, the Cochrane Library, Web of Science, PubMed, and EMBASE Database. Only randomized controlled trials of TCM interventions for ASD will be included. The Autism Diagnostic Observation Scale, Autism Diagnostic Interview-Revised, and Childhood Autism Rating Scale will be the primary outcome indicators. The methodological quality of this Bayesian-based network meta-analysis will be performed using the “Risk of Bias” tool. Stata 14.0 and WinBUGS 1.4.3 will be used to analyze the data. In addition, assessment of heterogeneity, inconsistency, subgroups, sensitivity, and publication bias will be conducted using the Cochrane Collaboration's tools. RESULTS: The results of this study will be submitted to a peer-reviewed journal for publication. CONCLUSION: This study will help patients recover better, provide clinical evidence for practitioners, and promote the use of TCM in ASD interventions. Lippincott Williams & Wilkins 2022-03-04 /pmc/articles/PMC8896422/ /pubmed/35244056 http://dx.doi.org/10.1097/MD.0000000000028957 Text en Copyright © 2022 the Author(s). Published by Wolters Kluwer Health, Inc. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License 4.0 (CCBY), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. http://creativecommons.org/licenses/by/4.0 (https://creativecommons.org/licenses/by/4.0/) |
spellingShingle | 3800 Feng, Xiang Li, Keshang Jiang, Quanrui Zhang, Yuxing Gong, Zhichao Zhi, Hui Yu, Jun Li, Wu Li, Jiangshan Traditional Chinese medicine intervention for autism spectrum disorders: A protocol for systematic review and network meta-analysis |
title | Traditional Chinese medicine intervention for autism spectrum disorders: A protocol for systematic review and network meta-analysis |
title_full | Traditional Chinese medicine intervention for autism spectrum disorders: A protocol for systematic review and network meta-analysis |
title_fullStr | Traditional Chinese medicine intervention for autism spectrum disorders: A protocol for systematic review and network meta-analysis |
title_full_unstemmed | Traditional Chinese medicine intervention for autism spectrum disorders: A protocol for systematic review and network meta-analysis |
title_short | Traditional Chinese medicine intervention for autism spectrum disorders: A protocol for systematic review and network meta-analysis |
title_sort | traditional chinese medicine intervention for autism spectrum disorders: a protocol for systematic review and network meta-analysis |
topic | 3800 |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8896422/ https://www.ncbi.nlm.nih.gov/pubmed/35244056 http://dx.doi.org/10.1097/MD.0000000000028957 |
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