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Enhancer–silencer transitions in the human genome

Dual-function regulatory elements (REs), acting as enhancers in some cellular contexts and as silencers in others, have been reported to facilitate the precise gene regulatory response to developmental signals in Drosophila melanogaster. However, with few isolated examples detected, dual-function RE...

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Detalles Bibliográficos
Autores principales: Huang, Di, Ovcharenko, Ivan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8896465/
https://www.ncbi.nlm.nih.gov/pubmed/35105669
http://dx.doi.org/10.1101/gr.275992.121