Cargando…

Hydrogen-oxygen therapy alleviates clinical symptoms in twelve patients hospitalized with COVID-19: A retrospective study of medical records

A global public health crisis caused by the 2019 novel coronavirus disease (COVID-19) leads to considerable morbidity and mortality, which bring great challenge to respiratory medicine. Hydrogen-oxygen therapy contributes to treat severe respiratory diseases and improve lung functions, yet there is...

Descripción completa

Detalles Bibliográficos
Autores principales: Luo, Peng, Ding, Yuanfang, He, Yuan, Chen, Dafeng, He, Qing, Huang, Zufeng, Huang, Shian, Lei, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8896485/
https://www.ncbi.nlm.nih.gov/pubmed/35244034
http://dx.doi.org/10.1097/MD.0000000000027759
_version_ 1784663177154265088
author Luo, Peng
Ding, Yuanfang
He, Yuan
Chen, Dafeng
He, Qing
Huang, Zufeng
Huang, Shian
Lei, Wei
author_facet Luo, Peng
Ding, Yuanfang
He, Yuan
Chen, Dafeng
He, Qing
Huang, Zufeng
Huang, Shian
Lei, Wei
author_sort Luo, Peng
collection PubMed
description A global public health crisis caused by the 2019 novel coronavirus disease (COVID-19) leads to considerable morbidity and mortality, which bring great challenge to respiratory medicine. Hydrogen-oxygen therapy contributes to treat severe respiratory diseases and improve lung functions, yet there is no information to support the clinical use of this therapy in the COVID-19 pneumonia. A retrospective study of medical records was carried out in Shishou Hospital of Traditional Chinese Medicine in Hubei, China. COVID-19 patients (aged ≥ 30 years) admitted to the hospital from January 29 to March 20, 2020 were subjected to control group (n = 12) who received routine therapy and case group (n = 12) who received additional hydrogen-oxygen therapy. The clinical characteristics of COVID-19 patients were analyzed. The physiological and biochemical indexes, including immune inflammation indicators, electrolytes, myocardial enzyme profile, and functions of liver and kidney, were examined and investigated before and after hydrogen-oxygen therapy. The results showed significant decreases in the neutrophil percentage and the concentration and abnormal proportion of C-reactive protein in COVID-19 patients received additional hydrogen-oxygen therapy. This novel therapeutic may alleviate clinical symptoms of COVID-19 patients by suppressing inflammation responses.
format Online
Article
Text
id pubmed-8896485
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher Lippincott Williams & Wilkins
record_format MEDLINE/PubMed
spelling pubmed-88964852022-03-07 Hydrogen-oxygen therapy alleviates clinical symptoms in twelve patients hospitalized with COVID-19: A retrospective study of medical records Luo, Peng Ding, Yuanfang He, Yuan Chen, Dafeng He, Qing Huang, Zufeng Huang, Shian Lei, Wei Medicine (Baltimore) 6600 A global public health crisis caused by the 2019 novel coronavirus disease (COVID-19) leads to considerable morbidity and mortality, which bring great challenge to respiratory medicine. Hydrogen-oxygen therapy contributes to treat severe respiratory diseases and improve lung functions, yet there is no information to support the clinical use of this therapy in the COVID-19 pneumonia. A retrospective study of medical records was carried out in Shishou Hospital of Traditional Chinese Medicine in Hubei, China. COVID-19 patients (aged ≥ 30 years) admitted to the hospital from January 29 to March 20, 2020 were subjected to control group (n = 12) who received routine therapy and case group (n = 12) who received additional hydrogen-oxygen therapy. The clinical characteristics of COVID-19 patients were analyzed. The physiological and biochemical indexes, including immune inflammation indicators, electrolytes, myocardial enzyme profile, and functions of liver and kidney, were examined and investigated before and after hydrogen-oxygen therapy. The results showed significant decreases in the neutrophil percentage and the concentration and abnormal proportion of C-reactive protein in COVID-19 patients received additional hydrogen-oxygen therapy. This novel therapeutic may alleviate clinical symptoms of COVID-19 patients by suppressing inflammation responses. Lippincott Williams & Wilkins 2022-03-04 /pmc/articles/PMC8896485/ /pubmed/35244034 http://dx.doi.org/10.1097/MD.0000000000027759 Text en Copyright © 2022 the Author(s). Published by Wolters Kluwer Health, Inc. https://creativecommons.org/licenses/by-nc/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution-Non Commercial License 4.0 (CCBY-NC), where it is permissible to download, share, remix, transform, and buildup the work provided it is properly cited. The work cannot be used commercially without permission from the journal. http://creativecommons.org/licenses/by-nc/4.0 (https://creativecommons.org/licenses/by-nc/4.0/) This article is made available via the PMC Open Access Subset for unrestricted re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the COVID-19 pandemic or until permissions are revoked in writing. Upon expiration of these permissions, PMC is granted a perpetual license to make this article available via PMC and Europe PMC, consistent with existing copyright protections.
spellingShingle 6600
Luo, Peng
Ding, Yuanfang
He, Yuan
Chen, Dafeng
He, Qing
Huang, Zufeng
Huang, Shian
Lei, Wei
Hydrogen-oxygen therapy alleviates clinical symptoms in twelve patients hospitalized with COVID-19: A retrospective study of medical records
title Hydrogen-oxygen therapy alleviates clinical symptoms in twelve patients hospitalized with COVID-19: A retrospective study of medical records
title_full Hydrogen-oxygen therapy alleviates clinical symptoms in twelve patients hospitalized with COVID-19: A retrospective study of medical records
title_fullStr Hydrogen-oxygen therapy alleviates clinical symptoms in twelve patients hospitalized with COVID-19: A retrospective study of medical records
title_full_unstemmed Hydrogen-oxygen therapy alleviates clinical symptoms in twelve patients hospitalized with COVID-19: A retrospective study of medical records
title_short Hydrogen-oxygen therapy alleviates clinical symptoms in twelve patients hospitalized with COVID-19: A retrospective study of medical records
title_sort hydrogen-oxygen therapy alleviates clinical symptoms in twelve patients hospitalized with covid-19: a retrospective study of medical records
topic 6600
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8896485/
https://www.ncbi.nlm.nih.gov/pubmed/35244034
http://dx.doi.org/10.1097/MD.0000000000027759
work_keys_str_mv AT luopeng hydrogenoxygentherapyalleviatesclinicalsymptomsintwelvepatientshospitalizedwithcovid19aretrospectivestudyofmedicalrecords
AT dingyuanfang hydrogenoxygentherapyalleviatesclinicalsymptomsintwelvepatientshospitalizedwithcovid19aretrospectivestudyofmedicalrecords
AT heyuan hydrogenoxygentherapyalleviatesclinicalsymptomsintwelvepatientshospitalizedwithcovid19aretrospectivestudyofmedicalrecords
AT chendafeng hydrogenoxygentherapyalleviatesclinicalsymptomsintwelvepatientshospitalizedwithcovid19aretrospectivestudyofmedicalrecords
AT heqing hydrogenoxygentherapyalleviatesclinicalsymptomsintwelvepatientshospitalizedwithcovid19aretrospectivestudyofmedicalrecords
AT huangzufeng hydrogenoxygentherapyalleviatesclinicalsymptomsintwelvepatientshospitalizedwithcovid19aretrospectivestudyofmedicalrecords
AT huangshian hydrogenoxygentherapyalleviatesclinicalsymptomsintwelvepatientshospitalizedwithcovid19aretrospectivestudyofmedicalrecords
AT leiwei hydrogenoxygentherapyalleviatesclinicalsymptomsintwelvepatientshospitalizedwithcovid19aretrospectivestudyofmedicalrecords