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CASCADE: high-throughput characterization of regulatory complex binding altered by non-coding variants

Non-coding DNA variants (NCVs) impact gene expression by altering binding sites for regulatory complexes. New high-throughput methods are needed to characterize the impact of NCVs on regulatory complexes. We developed CASCADE (Customizable Approach to Survey Complex Assembly at DNA Elements), an arr...

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Detalles Bibliográficos
Autores principales:	Bray, David, Hook, Heather, Zhao, Rose, Keenan, Jessica L., Penvose, Ashley, Osayame, Yemi, Mohaghegh, Nima, Chen, Xiaoting, Parameswaran, Sreeja, Kottyan, Leah C., Weirauch, Matthew T., Siggers, Trevor
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8896503/ https://www.ncbi.nlm.nih.gov/pubmed/35252945 http://dx.doi.org/10.1016/j.xgen.2022.100098

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