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Quantifying and correcting slide-to-slide variation in multiplexed immunofluorescence images
MOTIVATION: Multiplexed imaging is a nascent single-cell assay with a complex data structure susceptible to technical variability that disrupts inference. These in situ methods are valuable in understanding cell–cell interactions, but few standardized processing steps or normalization techniques of...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8896603/ https://www.ncbi.nlm.nih.gov/pubmed/34983062 http://dx.doi.org/10.1093/bioinformatics/btab877 |