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Quantifying and correcting slide-to-slide variation in multiplexed immunofluorescence images

MOTIVATION: Multiplexed imaging is a nascent single-cell assay with a complex data structure susceptible to technical variability that disrupts inference. These in situ methods are valuable in understanding cell–cell interactions, but few standardized processing steps or normalization techniques of...

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Detalles Bibliográficos
Autores principales: Harris, Coleman R, McKinley, Eliot T, Roland, Joseph T, Liu, Qi, Shrubsole, Martha J, Lau, Ken S, Coffey, Robert J, Wrobel, Julia, Vandekar, Simon N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8896603/
https://www.ncbi.nlm.nih.gov/pubmed/34983062
http://dx.doi.org/10.1093/bioinformatics/btab877

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