Preclinical evaluation of a protracted GLP-1/glucagon receptor co-agonist: Translational difficulties and pitfalls

During recent years combining GLP-1 and glucagon receptor agonism with the purpose of achieving superior weight loss and metabolic control compared to GLP-1 alone has received much attention. The superior efficacy has been shown by several in preclinical models but has been difficult to reproduce in...

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Detalles Bibliográficos
Autores principales: Simonsen, Lotte, Lau, Jesper, Kruse, Thomas, Guo, Tingqing, McGuire, Jim, Jeppesen, Jacob Fuglsbjerg, Niss, Kristoffer, Sauerberg, Per, Raun, Kirsten, Dornonville de la Cour, Charlotta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8896685/
https://www.ncbi.nlm.nih.gov/pubmed/35245328
http://dx.doi.org/10.1371/journal.pone.0264974

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