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Specific mesoderm subset derived from human pluripotent stem cells ameliorates microvascular pathology in type 2 diabetic mice

Human induced pluripotent stem cells (hiPSCs) were differentiated into a specific mesoderm subset characterized by KDR(+)CD56(+)APLNR(+) (KNA(+)) expression. KNA(+) cells had high clonal proliferative potential and specification into endothelial colony-forming cell (ECFCs) phenotype. KNA(+) cells di...

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Detalles Bibliográficos
Autores principales:	Gil, Chang-Hyun, Chakraborty, Dibyendu, Vieira, Cristiano P., Prasain, Nutan, Calzi, Sergio Li, Fortmann, Seth D., Hu, Ping, Banno, Kimihiko, Jamal, Mohamed, Huang, Chao, Sielski, Micheli S., Lin, Yang, Huang, Xinxin, Dupont, Mariana D., Floyd, Jason L., Prasad, Ram, Longhini, Ana Leda F., McGill, Trevor J., Chung, Hyung-Min, Murphy, Michael P., Kotton, Darrell N., Boulton, Michael E., Yoder, Mervin C., Grant, Maria B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Association for the Advancement of Science 2022
Materias:	Biomedicine and Life Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8896785/ https://www.ncbi.nlm.nih.gov/pubmed/35245116 http://dx.doi.org/10.1126/sciadv.abm5559

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