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Structure of the Wilson disease copper transporter ATP7B

ATP7A and ATP7B, two homologous copper-transporting P1B-type ATPases, play crucial roles in cellular copper homeostasis, and mutations cause Menkes and Wilson diseases, respectively. ATP7A/B contains a P-type ATPase core consisting of a membrane transport domain and three cytoplasmic domains, the A,...

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Detalles Bibliográficos
Autores principales:	Bitter, Ryan M., Oh, SeCheol, Deng, Zengqin, Rahman, Suhaila, Hite, Richard K., Yuan, Peng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Association for the Advancement of Science 2022
Materias:	Biomedicine and Life Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8896786/ https://www.ncbi.nlm.nih.gov/pubmed/35245129 http://dx.doi.org/10.1126/sciadv.abl5508

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