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Cell type–specific mechanism of Setd1a heterozygosity in schizophrenia pathogenesis

Schizophrenia (SCZ) is a chronic, serious mental disorder. Although more than 200 SCZ-associated genes have been identified, the underlying molecular and cellular mechanisms remain largely unknown. Here, we generated a Setd1a (SET domain containing 1A) haploinsufficiency mouse model to understand ho...

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Detalles Bibliográficos
Autores principales:	Chen, Renchao, Liu, Yiqiong, Djekidel, Mohamed N., Chen, Wenqiang, Bhattacherjee, Aritra, Chen, Zhiyuan, Scolnick, Ed, Zhang, Yi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Association for the Advancement of Science 2022
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8896793/ https://www.ncbi.nlm.nih.gov/pubmed/35245111 http://dx.doi.org/10.1126/sciadv.abm1077

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