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The oxygen sensor prolyl hydroxylase domain 2 regulates the in vivo suppressive capacity of regulatory T cells

The oxygen sensor prolyl hydroxylase domain 2 (PHD2) plays an important role in cell hypoxia adaptation by regulating the stability of HIF proteins (HIF1α and HIF2α) in numerous cell types, including T lymphocytes. The role of oxygen sensor on immune cells, particularly on regulatory T cell (Treg) f...

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Detalles Bibliográficos
Autores principales:	Ajouaou, Yousra, Azouz, Abdulkader, Taquin, Anaëlle, Denanglaire, Sebastien, Hussein, Hind, Krayem, Mohammad, Andris, Fabienne, Moser, Muriel, Goriely, Stanislas, Leo, Oberdan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2022
Materias:	Immunology and Inflammation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8896828/ https://www.ncbi.nlm.nih.gov/pubmed/35192456 http://dx.doi.org/10.7554/eLife.70555

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