Epigenetic reprogramming by TET enzymes impacts co-transcriptional R-loops

DNA oxidation by ten-eleven translocation (TET) family enzymes is essential for epigenetic reprogramming. The conversion of 5-methylcytosine (5mC) into 5-hydroxymethylcytosine (5hmC) initiates developmental and cell-type-specific transcriptional programs through mechanisms that include changes in th...

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Detalles Bibliográficos
Autores principales: Sabino, João C, de Almeida, Madalena R, Abreu, Patrícia L, Ferreira, Ana M, Caldas, Paulo, Domingues, Marco M, Santos, Nuno C, Azzalin, Claus M, Grosso, Ana Rita, de Almeida, Sérgio Fernandes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Chromosomes and Gene Expression
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8896830/
https://www.ncbi.nlm.nih.gov/pubmed/35191837
http://dx.doi.org/10.7554/eLife.69476

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8896830/
https://www.ncbi.nlm.nih.gov/pubmed/35191837
http://dx.doi.org/10.7554/eLife.69476

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