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An Unusual Case of Chronic Lymphocytic Leukaemia Involving the Cervix
Chronic lymphocytic leukaemia (CLL) is a malignant monoclonal expansion of B lymphocytes, with accumulation of abnormal lymphocytes in the blood, bone marrow, spleen, lymph nodes and liver. It is mainly a disease of the elderly population. Though extra-nodal involvement is common, cervical and vulvo...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cureus
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8896842/ https://www.ncbi.nlm.nih.gov/pubmed/35291544 http://dx.doi.org/10.7759/cureus.21823 |
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author | Hamer, Jack Alazizi, Maher Tahmasebi, Farshad |
author_facet | Hamer, Jack Alazizi, Maher Tahmasebi, Farshad |
author_sort | Hamer, Jack |
collection | PubMed |
description | Chronic lymphocytic leukaemia (CLL) is a malignant monoclonal expansion of B lymphocytes, with accumulation of abnormal lymphocytes in the blood, bone marrow, spleen, lymph nodes and liver. It is mainly a disease of the elderly population. Though extra-nodal involvement is common, cervical and vulvovaginal involvement by CLL is particularly uncommon. In this case report, we discuss the case of cervical involvement of CLL in an 84-year-old patient who presented to rapid-access gynaecological clinic following concerns of persistent postmenopausal bleeding. Previously the patient was known to haematology with a well-controlled diagnosis of CLL since 2007. The initial examination was significant for an enlarged, irregular cervix, whereby a punch biopsy was then obtained. Histological analysis revealed evidence of CLL within the cervix. |
format | Online Article Text |
id | pubmed-8896842 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Cureus |
record_format | MEDLINE/PubMed |
spelling | pubmed-88968422022-03-14 An Unusual Case of Chronic Lymphocytic Leukaemia Involving the Cervix Hamer, Jack Alazizi, Maher Tahmasebi, Farshad Cureus Obstetrics/Gynecology Chronic lymphocytic leukaemia (CLL) is a malignant monoclonal expansion of B lymphocytes, with accumulation of abnormal lymphocytes in the blood, bone marrow, spleen, lymph nodes and liver. It is mainly a disease of the elderly population. Though extra-nodal involvement is common, cervical and vulvovaginal involvement by CLL is particularly uncommon. In this case report, we discuss the case of cervical involvement of CLL in an 84-year-old patient who presented to rapid-access gynaecological clinic following concerns of persistent postmenopausal bleeding. Previously the patient was known to haematology with a well-controlled diagnosis of CLL since 2007. The initial examination was significant for an enlarged, irregular cervix, whereby a punch biopsy was then obtained. Histological analysis revealed evidence of CLL within the cervix. Cureus 2022-02-01 /pmc/articles/PMC8896842/ /pubmed/35291544 http://dx.doi.org/10.7759/cureus.21823 Text en Copyright © 2022, Hamer et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Obstetrics/Gynecology Hamer, Jack Alazizi, Maher Tahmasebi, Farshad An Unusual Case of Chronic Lymphocytic Leukaemia Involving the Cervix |
title | An Unusual Case of Chronic Lymphocytic Leukaemia Involving the Cervix |
title_full | An Unusual Case of Chronic Lymphocytic Leukaemia Involving the Cervix |
title_fullStr | An Unusual Case of Chronic Lymphocytic Leukaemia Involving the Cervix |
title_full_unstemmed | An Unusual Case of Chronic Lymphocytic Leukaemia Involving the Cervix |
title_short | An Unusual Case of Chronic Lymphocytic Leukaemia Involving the Cervix |
title_sort | unusual case of chronic lymphocytic leukaemia involving the cervix |
topic | Obstetrics/Gynecology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8896842/ https://www.ncbi.nlm.nih.gov/pubmed/35291544 http://dx.doi.org/10.7759/cureus.21823 |
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