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Advances in Endoscopic Photoacoustic Imaging
Photoacoustic (PA) imaging is able to provide extremely high molecular contrast while maintaining the superior imaging depth of ultrasound (US) imaging. Conventional microscopic PA imaging has limited access to deeper tissue due to strong light scattering and attenuation. Endoscopic PA technology en...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8896876/ https://www.ncbi.nlm.nih.gov/pubmed/35252433 http://dx.doi.org/10.3390/photonics8070281 |
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author | Li, Yan Lu, Gengxi Zhou, Qifa Chen, Zhongping |
author_facet | Li, Yan Lu, Gengxi Zhou, Qifa Chen, Zhongping |
author_sort | Li, Yan |
collection | PubMed |
description | Photoacoustic (PA) imaging is able to provide extremely high molecular contrast while maintaining the superior imaging depth of ultrasound (US) imaging. Conventional microscopic PA imaging has limited access to deeper tissue due to strong light scattering and attenuation. Endoscopic PA technology enables direct delivery of excitation light into the interior of a hollow organ or cavity of the body for functional and molecular PA imaging of target tissue. Various endoscopic PA probes have been developed for different applications, including the intravascular imaging of lipids in atherosclerotic plaque and endoscopic imaging of colon cancer. In this paper, the authors review representative probe configurations and corresponding preclinical applications. In addition, the potential challenges and future directions of endoscopic PA imaging are discussed. |
format | Online Article Text |
id | pubmed-8896876 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
record_format | MEDLINE/PubMed |
spelling | pubmed-88968762022-07-16 Advances in Endoscopic Photoacoustic Imaging Li, Yan Lu, Gengxi Zhou, Qifa Chen, Zhongping Photonics Article Photoacoustic (PA) imaging is able to provide extremely high molecular contrast while maintaining the superior imaging depth of ultrasound (US) imaging. Conventional microscopic PA imaging has limited access to deeper tissue due to strong light scattering and attenuation. Endoscopic PA technology enables direct delivery of excitation light into the interior of a hollow organ or cavity of the body for functional and molecular PA imaging of target tissue. Various endoscopic PA probes have been developed for different applications, including the intravascular imaging of lipids in atherosclerotic plaque and endoscopic imaging of colon cancer. In this paper, the authors review representative probe configurations and corresponding preclinical applications. In addition, the potential challenges and future directions of endoscopic PA imaging are discussed. 2021-07 2021-07-16 /pmc/articles/PMC8896876/ /pubmed/35252433 http://dx.doi.org/10.3390/photonics8070281 Text en https://creativecommons.org/licenses/by/4.0/This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Li, Yan Lu, Gengxi Zhou, Qifa Chen, Zhongping Advances in Endoscopic Photoacoustic Imaging |
title | Advances in Endoscopic Photoacoustic Imaging |
title_full | Advances in Endoscopic Photoacoustic Imaging |
title_fullStr | Advances in Endoscopic Photoacoustic Imaging |
title_full_unstemmed | Advances in Endoscopic Photoacoustic Imaging |
title_short | Advances in Endoscopic Photoacoustic Imaging |
title_sort | advances in endoscopic photoacoustic imaging |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8896876/ https://www.ncbi.nlm.nih.gov/pubmed/35252433 http://dx.doi.org/10.3390/photonics8070281 |
work_keys_str_mv | AT liyan advancesinendoscopicphotoacousticimaging AT lugengxi advancesinendoscopicphotoacousticimaging AT zhouqifa advancesinendoscopicphotoacousticimaging AT chenzhongping advancesinendoscopicphotoacousticimaging |