Hydrostatic Pressure Controls Angiogenesis Through Endothelial YAP1 During Lung Regeneration

Pulmonary artery (PA) pressure increases during lung growth after unilateral pneumonectomy (PNX). Mechanosensitive transcriptional co-activator, yes-associated protein (YAP1), in endothelial cells (ECs) is necessary for angiogenesis during post-PNX lung growth. We investigate whether increases in PA...

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Detalles Bibliográficos
Autores principales: Mammoto, Tadanori, Hunyenyiwa, Tendai, Kyi, Priscilla, Hendee, Kathryn, Matus, Kienna, Rao, Sridhar, Lee, Sang H., Tabima, Diana M., Chesler, Naomi C., Mammoto, Akiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Bioengineering and Biotechnology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8896883/
https://www.ncbi.nlm.nih.gov/pubmed/35252132
http://dx.doi.org/10.3389/fbioe.2022.823642

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