Histone deacetylase inhibitors inhibit cervical cancer growth through Parkin acetylation-mediated mitophagy

Parkin, an E3 ubiquitin ligase, plays a role in maintaining mitochondrial homeostasis through targeting damaged mitochondria for mitophagy. Accumulating evidence suggests that the acetylation modification of the key mitophagy machinery influences mitophagy level, but the underlying mechanism is poor...

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Detalles Bibliográficos
Autores principales: Sun, Xin, Shu, Yuhan, Ye, Guiqin, Wu, Caixia, Xu, Mengting, Gao, Ruilan, Huang, Dongsheng, Zhang, Jianbin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8897022/
https://www.ncbi.nlm.nih.gov/pubmed/35256949
http://dx.doi.org/10.1016/j.apsb.2021.07.003

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