Understanding the physiological functions of the host xenobiotic-sensing nuclear receptors PXR and CAR on the gut microbiome using genetically modified mice

Pharmacological activation of the xenobiotic-sensing nuclear receptors pregnane X receptor (PXR) and constitutive androstane receptor (CAR) is well-known to increase drug metabolism and reduce inflammation. Little is known regarding their physiological functions on the gut microbiome. In this study,...

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Detalles Bibliográficos
Autores principales: Little, Mallory, Dutta, Moumita, Li, Hao, Matson, Adam, Shi, Xiaojian, Mascarinas, Gabby, Molla, Bruk, Weigel, Kris, Gu, Haiwei, Mani, Sridhar, Cui, Julia Yue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8897037/
https://www.ncbi.nlm.nih.gov/pubmed/35256948
http://dx.doi.org/10.1016/j.apsb.2021.07.022

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8897037/
https://www.ncbi.nlm.nih.gov/pubmed/35256948
http://dx.doi.org/10.1016/j.apsb.2021.07.022

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