Ferroptosis is essential for diabetic cardiomyopathy and is prevented by sulforaphane via AMPK/NRF2 pathways

Herein, we define the role of ferroptosis in the pathogenesis of diabetic cardiomyopathy (DCM) by examining the expression of key regulators of ferroptosis in mice with DCM and a new ex vivo DCM model. Advanced glycation end-products (AGEs), an important pathogenic factor of DCM, were found to induc...

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Detalles Bibliográficos
Autores principales: Wang, Xiang, Chen, Xinxin, Zhou, Wenqian, Men, Hongbo, Bao, Terigen, Sun, Yike, Wang, Quanwei, Tan, Yi, Keller, Bradley B., Tong, Qian, Zheng, Yang, Cai, Lu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8897044/
https://www.ncbi.nlm.nih.gov/pubmed/35256941
http://dx.doi.org/10.1016/j.apsb.2021.10.005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8897044/
https://www.ncbi.nlm.nih.gov/pubmed/35256941
http://dx.doi.org/10.1016/j.apsb.2021.10.005

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