Cargando…

De novo expression of gastrokines in pancreatic precursor lesions impede the development of pancreatic cancer

Molecular events occurring in stepwise progression from pre-malignant lesions (pancreatic intraepithelial neoplasia; PanIN) to the development of pancreatic ductal adenocarcinoma (PDAC) are poorly understood. Thus, characterization of early PanIN lesions may reveal markers that can help in diagnosin...

Descripción completa

Detalles Bibliográficos
Autores principales:	Steiner, Sabrina, Seleznik, Gitta M., Reding, Theresia, Stopic, Matea, Lenggenhager, Daniela, ten Buren, Emiel, Eshmuminov, Dilmurodjon, Endhardt, Katharina, Hagedorn, Catherine, Heidenblut, Anna M., Bratus-Neuenschwander, Anna, Grossmann, Jonas, Trachsel, Christian, Jabbar, Karolina S., Hahn, Stephan A., Berg, Johannes vom, Graf, Rolf, Gupta, Anurag
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8897191/ https://www.ncbi.nlm.nih.gov/pubmed/35082384 http://dx.doi.org/10.1038/s41388-022-02182-4

Ejemplares similares

The pancreas responds to remote damage and systemic stress by secretion of the pancreatic secretory proteins PSP/regI and PAP/regIII
por: Reding, Theresia, et al.
Publicado: (2017)

ASO Author Reflections: Chemotherapy Regimen in Borderline Resectable and Locally Advanced Pancreatic Cancer—Resection Cuts the Deal
por: Eshmuminov, Dilmurodjon, et al.
Publicado: (2023)

Orchestrating Treatment Modalities in Metastatic Pancreatic Neuroendocrine Tumors—Need for a Conductor
por: Siebenhüner, Alexander R., et al.
Publicado: (2022)

The Role of Gastrokine 1 in Gastric Cancer
por: Yoon, Jung Hwan, et al.
Publicado: (2014)

The role and diagnostic potential of gastrokine 1 in gastric cancer
por: Koper-Lenkiewicz, Olga M, et al.
Publicado: (2019)

Enhanced proliferation of pancreatic acinar cells in MRL/MpJ mice is driven by severe acinar injury but independent of inflammation
por: Bombardo, Marta, et al.
Publicado: (2018)

β(6)-Integrin Serves as a Potential Serum Marker for Diagnosis and Prognosis of Pancreatic Adenocarcinoma
por: Lenggenhager, Daniela, et al.
Publicado: (2021)

Epigenetic alterations of gastrokine 1 gene expression in gastric cancer
por: Altieri, Filomena, et al.
Publicado: (2017)

Biochemical Properties of Gastrokine-1 Purified from Chicken Gizzard Smooth Muscle
por: Hnia, Karim, et al.
Publicado: (2008)

Gastrokine 1 mRNA in human sera is not informative biomarker for gastric cancer
por: Villano, Valentina, et al.
Publicado: (2016)

The diagnostic value of serum gastrokine 1 (GKN1) protein in gastric cancer
por: Yoon, Jung Hwan, et al.
Publicado: (2019)

Low‐level gastrokine 2 promoted progress of NSCLC and as a potential biomarker
por: Yang, Xiang, et al.
Publicado: (2021)

Gastrokine 1 induces senescence and apoptosis through regulating telomere length in gastric cancer
por: Yoon, Jung Hwan, et al.
Publicado: (2014)

Gastrokine-1, an anti-amyloidogenic protein secreted by the stomach, regulates diet-induced obesity
por: Overstreet, Anne-Marie C., et al.
Publicado: (2021)

EBNA1 binding and epigenetic regulation of gastrokine tumor suppressor genes in gastric carcinoma cells
por: Lu, Fang, et al.
Publicado: (2014)

Gastrokine 1 Expression in the Human Gastric Mucosa Is Closely Associated with the Degree of Gastritis and DNA Methylation
por: Choi, Won Suk, et al.
Publicado: (2013)

Effects of gastrokine-2 expression on gastric cancer cell apoptosis by activation of extrinsic apoptotic pathways
por: SHI, LIN-SEN, et al.
Publicado: (2014)

Gastrokine 2 Regulates the Antitumor Effect of JAK2/STAT3 Pathway in Gastric Cancer
por: Zhou, Yu, et al.
Publicado: (2021)

Gastric cancer with positive peritoneal cytology: survival benefit after induction chemotherapy and conversion to negative peritoneal cytology
por: Valletti, Massimiliano, et al.
Publicado: (2021)

Serum procalcitonin improves diagnosis of infectious complications after CRS/HIPEC
por: Roth, Lilian, et al.
Publicado: (2023)

The transcriptome response of the ruminal methanogen Methanobrevibacter ruminantium strain M1 to the inhibitor lauric acid
por: Zhou, Xuan, et al.
Publicado: (2018)

Retracted: Gastrokine 2 Regulates the Antitumor Effect of JAK2/STAT3 Pathway in Gastric Cancer
por: and Alternative Medicine, Evidence-Based Complementary
Publicado: (2023)

A comprehensive examination of Nanopore native RNA sequencing for characterization of complex transcriptomes
por: Soneson, Charlotte, et al.
Publicado: (2019)

The Role of Pancreatic Stone Protein (PSP) as a Biomarker of Pregnancy-Related Diseases
por: Brun, Romana, et al.
Publicado: (2023)

Commonly Used Pancreatic Stellate Cell Cultures Differ Phenotypically and in Their Interactions with Pancreatic Cancer Cells
por: Lenggenhager, Daniela, et al.
Publicado: (2019)

Downregulation of gastrokine-1 in gastric cancer tissues and restoration of its expression induced gastric cancer cells to apoptosis
por: Mao, Wei, et al.
Publicado: (2012)

Serum Pancreatic Stone Protein Reference Values in Healthy Pregnant Women: A Prospective Cohort Study
por: Vonzun, Ladina, et al.
Publicado: (2023)

Loss of LAT1 sex-dependently delays recovery after caerulein-induced acute pancreatitis
por: Hagen, Cristina M, et al.
Publicado: (2022)

Analysis of Pain and Analgesia Protocols in Acute Cerulein-Induced Pancreatitis in Male C57BL/6 Mice
por: Durst, Mattea, et al.
Publicado: (2021)

Prognostic Value of Gastrokine-2 (GKN2) and Its Correlation with Tumor-Infiltrating Immune Cells in Lung Cancer and Gastric Cancers
por: Liu, Fangteng, et al.
Publicado: (2020)

(18)FDG-PET-CT identifies histopathological non-responders after neoadjuvant chemotherapy in locally advanced gastric and cardia cancer: cohort study
por: Schneider, Paul M., et al.
Publicado: (2018)

Pain-Associated Transcriptome Changes in Synovium of Knee Osteoarthritis Patients
por: Bratus-Neuenschwander, Anna, et al.
Publicado: (2018)

An integrated perfusion machine preserves injured human livers for 1 week
por: Eshmuminov, Dilmurodjon, et al.
Publicado: (2020)

Hyperoxia in portal vein causes enhanced vasoconstriction in arterial vascular bed
por: Eshmuminov, Dilmurodjon, et al.
Publicado: (2020)

Morphological Heterogeneity in Pancreatic Cancer Reflects Structural and Functional Divergence
por: Sántha, Petra, et al.
Publicado: (2021)

Left renal vein graft and in situ hepatic perfusion in hepatectomy for complete tumor invasion of hepatic veins: hemodynamic optimization and surgical technique
por: Lopez-Lopez, Víctor, et al.
Publicado: (2022)

Drug screening and genome editing in human pancreatic cancer organoids identifies drug-gene interactions and candidates for off-label therapy
por: Hirt, Christian K., et al.
Publicado: (2022)

Nutritional and Metabolic Derangements in Pancreatic Cancer and Pancreatic Resection
por: Gilliland, Taylor M., et al.
Publicado: (2017)

Accuracy of pancreatic stone protein for the diagnosis of infection in hospitalized adults: a systematic review and individual patient level meta-analysis
por: Prazak, Josef, et al.
Publicado: (2021)

Discriminative performance of pancreatic stone protein in predicting ICU mortality and infection severity in adult patients with infection: a systematic review and individual patient level meta-analysis
por: Zuercher, Patrick, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_3kiflmqc8co8a2q6v1j3m7n892