Oxygen-sensitive methylation of ULK1 is required for hypoxia-induced autophagy

Hypoxia is a physiological stress that frequently occurs in solid tissues. Autophagy, a ubiquitous degradation/recycling system in eukaryotic cells, renders cells tolerant to multiple stressors. However, the mechanisms underlying autophagy initiation upon hypoxia remains unclear. Here we show that p...

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Detalles Bibliográficos
Autores principales: Li, Jingyi, Zhang, Tao, Ren, Tao, Liao, Xiaoyu, Hao, Yilong, Lim, Je Sun, Lee, Jong-Ho, Li, Mi, Shao, Jichun, Liu, Rui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8897422/
https://www.ncbi.nlm.nih.gov/pubmed/35246531
http://dx.doi.org/10.1038/s41467-022-28831-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8897422/
https://www.ncbi.nlm.nih.gov/pubmed/35246531
http://dx.doi.org/10.1038/s41467-022-28831-6

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