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Expression of Neighbor of Punc E11 (NOPE) in early stage esophageal adenocarcinoma is associated with reduced survival

Current recommendations suggest neoadjuvant treatment in node-positive esophageal cancer or tumors staged T3 and upwards but some T2 N0 patients might benefit from neoadjuvant therapy. It is of clinical relevance to identify this subgroup. Loss of epithelial apicobasal polarity is a key factor in th...

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Detalles Bibliográficos
Autores principales: Kütting, Fabian, Gebauer, Florian, Zweerink, Susanne, Krämer, Laurenz, Schramm, Christoph, Quaas, Alexander, Bruns, Christiane, Goeser, Tobias, Nierhoff, Dirk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8897453/
https://www.ncbi.nlm.nih.gov/pubmed/35246597
http://dx.doi.org/10.1038/s41598-022-07580-y

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