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Edonerpic maleate regulates glutamate receptors through CRMP2- and Arc-mediated mechanisms in response to brain trauma

Dysfunction of ionotropic glutamate receptors (iGluRs) is a key molecular mechanism of excitotoxic neuronal injury following traumatic brain injury (TBI). Edonerpic maleate is a low molecular-weight compound that was screened as a candidate neuroprotective agent. In this study, we investigated its e...

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Detalles Bibliográficos
Autores principales: Chen, Tao, Yang, Li-Kun, Ai, Pu, Zhu, Jie, Hang, Chun-Hua, Wang, Yu-Hai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8897457/
https://www.ncbi.nlm.nih.gov/pubmed/35246523
http://dx.doi.org/10.1038/s41420-022-00901-0

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