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Intensive care unit capacity and mortality in older adults: a three nations retrospective observational cohort study

BACKGROUND: Intensive care unit (ICU) admissions among older adults are expected to increase, while the benefit remains uncertain. The availability of ICU beds varies between hospitals and between countries and is an important factor in the decision to admit older adults in the ICU. We aimed to asse...

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Autores principales: Abuhasira, Ran, Anstey, Matthew, Novack, Victor, Bose, Somnath, Talmor, Daniel, Fuchs, Lior
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8897522/
https://www.ncbi.nlm.nih.gov/pubmed/35244803
http://dx.doi.org/10.1186/s13613-022-00994-x
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author Abuhasira, Ran
Anstey, Matthew
Novack, Victor
Bose, Somnath
Talmor, Daniel
Fuchs, Lior
author_facet Abuhasira, Ran
Anstey, Matthew
Novack, Victor
Bose, Somnath
Talmor, Daniel
Fuchs, Lior
author_sort Abuhasira, Ran
collection PubMed
description BACKGROUND: Intensive care unit (ICU) admissions among older adults are expected to increase, while the benefit remains uncertain. The availability of ICU beds varies between hospitals and between countries and is an important factor in the decision to admit older adults in the ICU. We aimed to assess if a non-restrictive approach to ICU older adults admission is associated with a corresponding change in survival. METHODS: Retrospective cohort study that included patients ≥ 80 years who were admitted to each of the three participating hospitals in Australia, Israel, and the United States (USA), between the years 2006–2015, each with distinct ICU capacities and admission criteria. The primary outcomes were in-hospital mortality and all-cause mortality at 6, 12, 18, and 24 months following index hospitalization. RESULTS: The cohort included 62,866 patients with a mean age of 85.9 ± 4.6 years and 58.8% were women. The ICU admission rates were 22.5%, 2.6% and 2.3% in USA, Australia, and Israel, respectively. We constructed a model for ICU admissions based on the USA cohort (highest availability of ICU beds) and then calculated the expected probabilities for the Israeli and Australian cohorts. For the patients in the highest quintile of the admission model, actual ICU admission rates were 67.6% in USA, 22.1% in Australia and 6.0% in Israel. Of these, in-hospital death rates were 52.3% in Israel, 29.8% in Australia, and 22.1% in USA. Two years after hospital discharge, the survival rates in the USA and Australia were 53%, while in Israel 48%. CONCLUSION: ICU admission of adults ≥ 80 years is associated with increased in-hospital survival compared to ward admission, but survival rates 2 years later are similar. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s13613-022-00994-x.
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spelling pubmed-88975222022-03-08 Intensive care unit capacity and mortality in older adults: a three nations retrospective observational cohort study Abuhasira, Ran Anstey, Matthew Novack, Victor Bose, Somnath Talmor, Daniel Fuchs, Lior Ann Intensive Care Research BACKGROUND: Intensive care unit (ICU) admissions among older adults are expected to increase, while the benefit remains uncertain. The availability of ICU beds varies between hospitals and between countries and is an important factor in the decision to admit older adults in the ICU. We aimed to assess if a non-restrictive approach to ICU older adults admission is associated with a corresponding change in survival. METHODS: Retrospective cohort study that included patients ≥ 80 years who were admitted to each of the three participating hospitals in Australia, Israel, and the United States (USA), between the years 2006–2015, each with distinct ICU capacities and admission criteria. The primary outcomes were in-hospital mortality and all-cause mortality at 6, 12, 18, and 24 months following index hospitalization. RESULTS: The cohort included 62,866 patients with a mean age of 85.9 ± 4.6 years and 58.8% were women. The ICU admission rates were 22.5%, 2.6% and 2.3% in USA, Australia, and Israel, respectively. We constructed a model for ICU admissions based on the USA cohort (highest availability of ICU beds) and then calculated the expected probabilities for the Israeli and Australian cohorts. For the patients in the highest quintile of the admission model, actual ICU admission rates were 67.6% in USA, 22.1% in Australia and 6.0% in Israel. Of these, in-hospital death rates were 52.3% in Israel, 29.8% in Australia, and 22.1% in USA. Two years after hospital discharge, the survival rates in the USA and Australia were 53%, while in Israel 48%. CONCLUSION: ICU admission of adults ≥ 80 years is associated with increased in-hospital survival compared to ward admission, but survival rates 2 years later are similar. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s13613-022-00994-x. Springer International Publishing 2022-03-04 /pmc/articles/PMC8897522/ /pubmed/35244803 http://dx.doi.org/10.1186/s13613-022-00994-x Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Research
Abuhasira, Ran
Anstey, Matthew
Novack, Victor
Bose, Somnath
Talmor, Daniel
Fuchs, Lior
Intensive care unit capacity and mortality in older adults: a three nations retrospective observational cohort study
title Intensive care unit capacity and mortality in older adults: a three nations retrospective observational cohort study
title_full Intensive care unit capacity and mortality in older adults: a three nations retrospective observational cohort study
title_fullStr Intensive care unit capacity and mortality in older adults: a three nations retrospective observational cohort study
title_full_unstemmed Intensive care unit capacity and mortality in older adults: a three nations retrospective observational cohort study
title_short Intensive care unit capacity and mortality in older adults: a three nations retrospective observational cohort study
title_sort intensive care unit capacity and mortality in older adults: a three nations retrospective observational cohort study
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8897522/
https://www.ncbi.nlm.nih.gov/pubmed/35244803
http://dx.doi.org/10.1186/s13613-022-00994-x
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