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Early reduction of SARS-CoV-2-replication in bronchial epithelium by kinin B(2) receptor antagonism

ABSTRACT: SARS-CoV-2 has evolved to enter the host via the ACE2 receptor which is part of the kinin-kallikrein pathway. This complex pathway is only poorly understood in context of immune regulation but critical to control infection. This study examines SARS-CoV-2-infection and epithelial mechanisms...

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Detalles Bibliográficos
Autores principales: Jakwerth, Constanze A., Feuerherd, Martin, Guerth, Ferdinand M., Oelsner, Madlen, Schellhammer, Linda, Giglberger, Johanna, Pechtold, Lisa, Jerin, Claudia, Kugler, Luisa, Mogler, Carolin, Haller, Bernhard, Erb, Anna, Wollenberg, Barbara, Spinner, Christoph D., Buch, Thorsten, Protzer, Ulrike, Schmidt-Weber, Carsten B., Zissler, Ulrich M., Chaker, Adam M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8897552/
https://www.ncbi.nlm.nih.gov/pubmed/35247068
http://dx.doi.org/10.1007/s00109-022-02182-7