Meflin-positive cancer-associated fibroblasts enhance tumor response to immune checkpoint blockade

Cancer-associated fibroblasts (CAFs) are an integral component of the tumor microenvironment (TME). Most CAFs shape the TME toward an immunosuppressive milieu and attenuate the efficacy of immune checkpoint blockade (ICB) therapy. However, the detailed mechanism of how heterogeneous CAFs regulate tu...

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Detalles Bibliográficos
Autores principales: Miyai, Yuki, Sugiyama, Daisuke, Hase, Tetsunari, Asai, Naoya, Taki, Tetsuro, Nishida, Kazuki, Fukui, Takayuki, Chen-Yoshikawa, Toyofumi Fengshi, Kobayashi, Hiroki, Mii, Shinji, Shiraki, Yukihiro, Hasegawa, Yoshinori, Nishikawa, Hiroyoshi, Ando, Yuichi, Takahashi, Masahide, Enomoto, Atsushi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8897596/
https://www.ncbi.nlm.nih.gov/pubmed/35236758
http://dx.doi.org/10.26508/lsa.202101230

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