Unique mechanistic insights into pathways associated with the synergistic activity of polymyxin B and caspofungin against multidrug-resistant Klebsiella pneumoniae

Klebsiella pneumoniae is an opportunistic Gram-negative pathogen causing nosocomial infections. K. pneumoniae rapidly acquires antibiotic resistance and is known as a reservoir for resistance genes. Polymyxins remain effective as a last-line therapy against infections caused by multidrug-resistant (...

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Detalles Bibliográficos
Autores principales: Hussein, Maytham, Wong, Labell J.M., Zhao, Jinxin, Rees, Vanessa E., Allobawi, Rafah, Sharma, Rajnikant, Rao, Gauri G., Baker, Mark, Li, Jian, Velkov, Tony
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8897686/
https://www.ncbi.nlm.nih.gov/pubmed/35284046
http://dx.doi.org/10.1016/j.csbj.2022.02.021

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