Chronic exposure to the anti-M3 muscarinic acetylcholine receptor autoantibody in pemphigus vulgaris contributes to disease pathophysiology

Pemphigus vulgaris (PV) is a potentially lethal autoimmune mucocutaneous blistering disease characterized by binding of IgG autoantibodies (AuAbs) to keratinocytes (KCs). In addition to AuAbs against adhesion molecules desmogleins 1 and 3, PV patients also produce an AuAb against the M3 muscarinic a...

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Detalles Bibliográficos
Autores principales: Chernyavsky, Alex, Khylynskyi, Mykhailo M., Patel, Krupa G., Grando, Sergei A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8897697/
https://www.ncbi.nlm.nih.gov/pubmed/35143842
http://dx.doi.org/10.1016/j.jbc.2022.101687

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