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The renal cancer risk allele at 14q24.2 activates a novel hypoxia-inducible transcription factor-binding enhancer of DPF3 expression

Evolution of clear cell renal cell carcinoma is guided by dysregulation of hypoxia-inducible transcription factor (HIF) pathways following loss of the von Hippel-Lindau tumor suppressor protein. Renal cell carcinoma (RCC)-associated polymorphisms influence HIF–DNA interactions at enhancers of import...

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Detalles Bibliográficos
Autores principales:	Protze, Johanna, Naas, Stephanie, Krüger, René, Stöhr, Christine, Kraus, Andre, Grampp, Steffen, Wiesener, Michael, Schiffer, Mario, Hartmann, Arndt, Wullich, Bernd, Schödel, Johannes
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8897700/ https://www.ncbi.nlm.nih.gov/pubmed/35148991 http://dx.doi.org/10.1016/j.jbc.2022.101699

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