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Roles for the methyltransferase SETD8 in DNA damage repair

Epigenetic posttranslational modifications are critical for fine-tuning gene expression in various biological processes. SETD8 is so far the only known lysyl methyltransferase in mammalian cells to produce mono-methylation of histone H4 at lysine 20 (H4K20me1), a prerequisite for di- and tri-methyla...

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Detalles Bibliográficos
Autores principales:	Xu, Libo, Zhang, Ling, Sun, Jicheng, Hu, Xindan, Kalvakolanu, Dhan V., Ren, Hui, Guo, Baofeng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8897848/ https://www.ncbi.nlm.nih.gov/pubmed/35246238 http://dx.doi.org/10.1186/s13148-022-01251-5

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