Long noncoding RNA SNHG17: a novel molecule in human cancers

Many studies in recent years have found that dysregulation of long non-coding RNAs (lncRNAs) can contribute to disease. Small nucleolar RNA host gene 17 (SNHG17) is a novel cancer-related lncRNA of the SNHG family which is highly expressed in various tumors and may exert oncogenic functions. Several...

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Autores principales: Ma, Li, Gao, Jin, Zhang, Niu, Wang, Jiawei, Xu, Tianwei, Lei, Tianyao, Zou, Xiaoteng, Wei, Chenchen, Wang, Zhaoxia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8897953/
https://www.ncbi.nlm.nih.gov/pubmed/35248073
http://dx.doi.org/10.1186/s12935-022-02529-7
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author Ma, Li
Gao, Jin
Zhang, Niu
Wang, Jiawei
Xu, Tianwei
Lei, Tianyao
Zou, Xiaoteng
Wei, Chenchen
Wang, Zhaoxia
author_facet Ma, Li
Gao, Jin
Zhang, Niu
Wang, Jiawei
Xu, Tianwei
Lei, Tianyao
Zou, Xiaoteng
Wei, Chenchen
Wang, Zhaoxia
author_sort Ma, Li
collection PubMed
description Many studies in recent years have found that dysregulation of long non-coding RNAs (lncRNAs) can contribute to disease. Small nucleolar RNA host gene 17 (SNHG17) is a novel cancer-related lncRNA of the SNHG family which is highly expressed in various tumors and may exert oncogenic functions. Several studies have demonstrated that SNHG17 is closely related to the proliferation, migration, invasion, apoptosis, and chemical drug resistance of tumor cells, and clinical studies have found an association between high SNHG17 expression and poor prognosis. In this review, we summarize relevant studies investigating SNHG17, focusing on its biological function as well as its potential value for clinical applications.
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spelling pubmed-88979532022-03-16 Long noncoding RNA SNHG17: a novel molecule in human cancers Ma, Li Gao, Jin Zhang, Niu Wang, Jiawei Xu, Tianwei Lei, Tianyao Zou, Xiaoteng Wei, Chenchen Wang, Zhaoxia Cancer Cell Int Review Many studies in recent years have found that dysregulation of long non-coding RNAs (lncRNAs) can contribute to disease. Small nucleolar RNA host gene 17 (SNHG17) is a novel cancer-related lncRNA of the SNHG family which is highly expressed in various tumors and may exert oncogenic functions. Several studies have demonstrated that SNHG17 is closely related to the proliferation, migration, invasion, apoptosis, and chemical drug resistance of tumor cells, and clinical studies have found an association between high SNHG17 expression and poor prognosis. In this review, we summarize relevant studies investigating SNHG17, focusing on its biological function as well as its potential value for clinical applications. BioMed Central 2022-03-05 /pmc/articles/PMC8897953/ /pubmed/35248073 http://dx.doi.org/10.1186/s12935-022-02529-7 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Review
Ma, Li
Gao, Jin
Zhang, Niu
Wang, Jiawei
Xu, Tianwei
Lei, Tianyao
Zou, Xiaoteng
Wei, Chenchen
Wang, Zhaoxia
Long noncoding RNA SNHG17: a novel molecule in human cancers
title Long noncoding RNA SNHG17: a novel molecule in human cancers
title_full Long noncoding RNA SNHG17: a novel molecule in human cancers
title_fullStr Long noncoding RNA SNHG17: a novel molecule in human cancers
title_full_unstemmed Long noncoding RNA SNHG17: a novel molecule in human cancers
title_short Long noncoding RNA SNHG17: a novel molecule in human cancers
title_sort long noncoding rna snhg17: a novel molecule in human cancers
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8897953/
https://www.ncbi.nlm.nih.gov/pubmed/35248073
http://dx.doi.org/10.1186/s12935-022-02529-7
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