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Early administration of tocilizumab in hospitalized COVID-19 patients with elevated inflammatory markers; COVIDSTORM—a prospective, randomized, single-centre, open-label study
OBJECTIVES: Severe COVID-19 is associated with an imbalanced immune response. We hypothesized that patients with enhanced inflammation, as demonstrated by increased levels of certain inflammatory biomarkers, would benefit from interleukin-6 blockage. METHODS: Patients hospitalized with COVID-19, hyp...
Autores principales: | Broman, Niklas, Feuth, Thijs, Vuorinen, Tytti, Valtonen, Mika, Hohenthal, Ulla, Löyttyniemi, Eliisa, Hirvioja, Tiina, Jalava-Karvinen, Päivi, Marttila, Harri, Nordberg, Marika, Oksi, Jarmo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Author(s). Published by Elsevier Ltd on behalf of European Society of Clinical Microbiology and Infectious Diseases.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8897958/ https://www.ncbi.nlm.nih.gov/pubmed/35259529 http://dx.doi.org/10.1016/j.cmi.2022.02.027 |
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