Indoleamine 2,3‐dioxygenase (IDO)‐1 and IDO‐2 activity and severe course of COVID‐19

COVID‐19 is a pandemic with high morbidity and mortality. In an autopsy cohort of COVID‐19 patients, we found extensive accumulation of the tryptophan degradation products 3‐hydroxy‐anthranilic acid and quinolinic acid in the lungs, heart, and brain. This was not related to the expression of the try...

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Detalles Bibliográficos
Autores principales: Guo, Lihui, Schurink, Bernadette, Roos, Eva, Nossent, Esther J, Duitman, Jan Willem, Vlaar, Alexander PJ, van der Valk, Paul, Vaz, Frédéric M, Yeh, Syun‐Ru, Geeraerts, Zachary, Dijkhuis, Annemiek, van Vught, Lonneke, Bugiani, Marianna, Lutter, René
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2022
Materias:
Brief Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8897979/
https://www.ncbi.nlm.nih.gov/pubmed/34859884
http://dx.doi.org/10.1002/path.5842

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