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Subtotal Laryngectomy with Epiglottic Reconstruction for Glottic Carcinoma: A Single Institutional Experience

AIM: Laryngeal cancer is a common form of head and neck cancer in Vietnam where the current treatment is surgery. Subtotal laryngectomy with epiglottic reconstruction, a conservative surgery, allows removal of anterior commissure including thyroid cartilage and paraglottic space and provides a maxim...

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Autores principales: Le Minh, Ky, Nguyen Dinh, Phuc, Doan Thi Hong, Nhat, Pham Van, Huu, Nguyen Xuan, Quang, Nguyen Xuan, Hoa, Nguyen Thi To, Uyen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8898041/
https://www.ncbi.nlm.nih.gov/pubmed/35256858
http://dx.doi.org/10.2147/IJGM.S350624
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author Le Minh, Ky
Nguyen Dinh, Phuc
Doan Thi Hong, Nhat
Pham Van, Huu
Nguyen Xuan, Quang
Nguyen Xuan, Hoa
Nguyen Thi To, Uyen
author_facet Le Minh, Ky
Nguyen Dinh, Phuc
Doan Thi Hong, Nhat
Pham Van, Huu
Nguyen Xuan, Quang
Nguyen Xuan, Hoa
Nguyen Thi To, Uyen
author_sort Le Minh, Ky
collection PubMed
description AIM: Laryngeal cancer is a common form of head and neck cancer in Vietnam where the current treatment is surgery. Subtotal laryngectomy with epiglottic reconstruction, a conservative surgery, allows removal of anterior commissure including thyroid cartilage and paraglottic space and provides a maximum restoration of the anatomical structure of the larynx. PURPOSE: To evaluate the results, the safety and effectiveness of patients who were treated with subtotal laryngectomy with epiglottic reconstruction. MATERIAL AND METHOD: From January 2012 to July 2017, 42 patients (41 male, 1 female, median age 55.6 years, range 38–75 years) were diagnosed with glottic carcinomas at Vietnam National ENT Hospital, where they underwent a subtotal laryngectomy with epiglottic reconstruction. RESULTS: Thirty-one patients (73.8%) had T2 glottic carcinoma, 4 (9.5%) T3 glottic carcinoma, and 12 (25.6%) had neck dissection. The arytenoid cartilage on the tumor-bearing side was resected in 11 patients (26.2%). Functional ipsilateral neck dissection was performed in 30 patients. Positive lymph node of stage T2 was 1/31 (3.2%). Postoperative histopathologic examination showed a tumour free of resection margin in 41 patients (97.6%). Only one post-operative complication occurred with bleeding 24 hours after surgery. There was no mortality. The 3- and 5-year overall survival rates were 97.6% and 85.7%, respectively. The rate of local control was 92.9%. CONCLUSION: Subtotal laryngectomy with epiglottic reconstruction was performed mostly for T2 and certain T3 glottic carcinomas when there is difficult to safely remove the tumour with transoral laser microsurgery. This surgery appears to be effective for the overall survival and has potential in clinical practice for treating moderate glottic carcinoma.
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spelling pubmed-88980412022-03-06 Subtotal Laryngectomy with Epiglottic Reconstruction for Glottic Carcinoma: A Single Institutional Experience Le Minh, Ky Nguyen Dinh, Phuc Doan Thi Hong, Nhat Pham Van, Huu Nguyen Xuan, Quang Nguyen Xuan, Hoa Nguyen Thi To, Uyen Int J Gen Med Original Research AIM: Laryngeal cancer is a common form of head and neck cancer in Vietnam where the current treatment is surgery. Subtotal laryngectomy with epiglottic reconstruction, a conservative surgery, allows removal of anterior commissure including thyroid cartilage and paraglottic space and provides a maximum restoration of the anatomical structure of the larynx. PURPOSE: To evaluate the results, the safety and effectiveness of patients who were treated with subtotal laryngectomy with epiglottic reconstruction. MATERIAL AND METHOD: From January 2012 to July 2017, 42 patients (41 male, 1 female, median age 55.6 years, range 38–75 years) were diagnosed with glottic carcinomas at Vietnam National ENT Hospital, where they underwent a subtotal laryngectomy with epiglottic reconstruction. RESULTS: Thirty-one patients (73.8%) had T2 glottic carcinoma, 4 (9.5%) T3 glottic carcinoma, and 12 (25.6%) had neck dissection. The arytenoid cartilage on the tumor-bearing side was resected in 11 patients (26.2%). Functional ipsilateral neck dissection was performed in 30 patients. Positive lymph node of stage T2 was 1/31 (3.2%). Postoperative histopathologic examination showed a tumour free of resection margin in 41 patients (97.6%). Only one post-operative complication occurred with bleeding 24 hours after surgery. There was no mortality. The 3- and 5-year overall survival rates were 97.6% and 85.7%, respectively. The rate of local control was 92.9%. CONCLUSION: Subtotal laryngectomy with epiglottic reconstruction was performed mostly for T2 and certain T3 glottic carcinomas when there is difficult to safely remove the tumour with transoral laser microsurgery. This surgery appears to be effective for the overall survival and has potential in clinical practice for treating moderate glottic carcinoma. Dove 2022-03-01 /pmc/articles/PMC8898041/ /pubmed/35256858 http://dx.doi.org/10.2147/IJGM.S350624 Text en © 2022 Le Minh et al. https://creativecommons.org/licenses/by-nc/3.0/This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/ (https://creativecommons.org/licenses/by-nc/3.0/) ). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).
spellingShingle Original Research
Le Minh, Ky
Nguyen Dinh, Phuc
Doan Thi Hong, Nhat
Pham Van, Huu
Nguyen Xuan, Quang
Nguyen Xuan, Hoa
Nguyen Thi To, Uyen
Subtotal Laryngectomy with Epiglottic Reconstruction for Glottic Carcinoma: A Single Institutional Experience
title Subtotal Laryngectomy with Epiglottic Reconstruction for Glottic Carcinoma: A Single Institutional Experience
title_full Subtotal Laryngectomy with Epiglottic Reconstruction for Glottic Carcinoma: A Single Institutional Experience
title_fullStr Subtotal Laryngectomy with Epiglottic Reconstruction for Glottic Carcinoma: A Single Institutional Experience
title_full_unstemmed Subtotal Laryngectomy with Epiglottic Reconstruction for Glottic Carcinoma: A Single Institutional Experience
title_short Subtotal Laryngectomy with Epiglottic Reconstruction for Glottic Carcinoma: A Single Institutional Experience
title_sort subtotal laryngectomy with epiglottic reconstruction for glottic carcinoma: a single institutional experience
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8898041/
https://www.ncbi.nlm.nih.gov/pubmed/35256858
http://dx.doi.org/10.2147/IJGM.S350624
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