Novel Th17 Lymphocyte Populations, Th17.1 and PD1+Th17, are Increased in Takayasu Arteritis, and Both Th17 and Th17.1 Sub-Populations Associate with Active Disease

PURPOSE: We evaluated T helper lymphocyte profile, including novel Th17 subsets Th17.1 (secrete IFN-γ, associate with corticosteroid resistance) and PD1+Th17 (secrete TGF-β1, implicated in fibrosis), and related cytokines in peripheral blood of Takayasu arteritis (TAK). MATERIALS AND METHODS: We eva...

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Detalles Bibliográficos
Autores principales: Singh, Kritika, Rathore, Upendra, Rai, Mohit Kumar, Behera, Manas R, Jain, Neeraj, Ora, Manish, Bhadauria, Dharmendra, Sharma, Supriya, Pande, Gaurav, Gambhir, Sanjay, Nath, Alok, Kumar, Sudeep, Sharma, Aman, Agarwal, Vikas, Misra, Durga Prasanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2022
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8898181/
https://www.ncbi.nlm.nih.gov/pubmed/35256852
http://dx.doi.org/10.2147/JIR.S355881

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