Long-term Follow-up and Patterns of Response, Progression, and Hyperprogression in Patients after PD-1 Blockade in Advanced Sarcoma

PURPOSE: Programmed cell death protein 1 (PD-1) blockade can mediate objective responses in advanced sarcomas, but their durability has not been established and it is unclear if hyperprogressive disease (HPD) occurs in sarcomas treated with PD-1 inhibitors. EXPERIMENTAL DESIGN: We pooled patients wh...

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Detalles Bibliográficos
Autores principales: Klemen, Nicholas D., Hwang, Sinchun, Bradic, Martina, Rosenbaum, Evan, Dickson, Mark A., Gounder, Mrinal M., Kelly, Ciara M., Keohan, Mary L., Movva, Sujana, Thornton, Katherine A., Chi, Ping, Nacev, Benjamin A., Chan, Jason E., Bartlett, Edmund K., Richards, Allison L., Singer, Samuel, Donoghue, Mark T.A., Tap, William D., D'Angelo, Sandra P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2022
Materias:
Precision Medicine and Imaging
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8898277/
https://www.ncbi.nlm.nih.gov/pubmed/34965948
http://dx.doi.org/10.1158/1078-0432.CCR-21-3445

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