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Keap-NRF2 signaling contributes to the Notch1 protected heart against ischemic reperfusion injury via regulating mitochondrial ROS generation and bioenergetics

Myocardial ischemia/reperfusion (I/R) injury is recognized as the leading cause of death worldwide. However, the molecular mechanisms involved in this process are still not fully understood. We previously reported that the combined action of Notch1 and Keap1-NRF2 signaling pathway can significantly...

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Detalles Bibliográficos
Autores principales:	Xu, Hua, Wan, Xiao-dan, Zhu, Rong-rong, Liu, Jin-long, Liu, Ji-chun, Zhou, Xue-liang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Ivyspring International Publisher 2022
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8898363/ https://www.ncbi.nlm.nih.gov/pubmed/35280686 http://dx.doi.org/10.7150/ijbs.63297

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